100L Pilot Scale Rotary Evaporator

The 100L rotary evaporator bridges the gap between benchtop laboratory units and industrial distillation plants. It is designed specifically for chemical and pharmaceutical process development, enabling engineers to verify process parameters, ensure safety compliance, and evaluate solvent recovery rates before full-scale commercial production.

Designed for continuous pilot-scale runs, this system utilizes a 100-liter evaporation flask to handle bulk solvent stripping under controlled thermal and vacuum conditions.

100L Capacity for Linear Scale-Up Data
Laboratory-scale fluid dynamics and thermal behaviors do not scale linearly. The 100L flask provides a representative working volume to generate reliable pilot data, drastically reducing the number of repeated trials.
• Applications: Active Pharmaceutical Ingredient (API) concentration, organic solvent recovery, and natural botanical extraction.
• Process Verification: Allows accurate monitoring of batch concentration times and thermal exposure limits.

Film Evaporation for Heat-Sensitive Compounds
The system uses adjustable flask rotation (10 to 110 RPM) to force liquid across the inner wall, creating a continuous thin film. This maximizing of surface area accelerates distillation compared to static jacketed reactors.
• Thermal Protection: Uniform film distribution eliminates localized hot spots, minimizing the risk of thermal degradation for sensitive intermediates.

Vacuum-Tight Sealing Matrix
Equipped with a dual-layer PTFE and Viton mechanical seal, the system maintains stable vacuum levels down to less than 1 mbar. Lowering the system pressure depresses the boiling point of targeted solvents, allowing distillation to occur at lower bath temperatures.

Certified Explosion-Proof (Ex) Engineering Options
For facilities processing flammable organic solvents (such as Ethanol, Hexane, or Acetone), the system can be configured with specialized safety components:
ATEX / IECEx Certified induction motors and electronic control enclosures.
SUS304 stainless steel supporting frame with heavy-duty locked casters for structural stability during high-torque rotation.
Motorized automatic lift mechanism to safely raise and lower the 100L flask.

Dual-Condenser Architecture with Non-Stop Collection
To manage high vapor volumes without bottlenecking, the distillation vapor pathway is optimized for efficiency:
• Dual Condenser: A vertical triple-coil main condenser paired with an auxiliary condenser prevents vapor bypass into the vacuum line.
• Continuous Draining: The 50L receiving configuration utilizes isolation valves. Operators can drain recovered solvents from the collection flask without breaking the system vacuum, preventing process downtime.

We supply direct from our manufacturing facility, supporting global industrial standards and distributor requirements:

Electrical Adaptability: Tailored voltage setups including 110V/220V single-phase, or 380V/415V 3-phase (50/60Hz).

Logistics Packaging: All glass assemblies and mechanical parts are packed in individual foam molds inside fumigation-free plywood crates for safe sea/air freight.

Distributor Support: Supply includes full technical schematics, English operational manuals, and dedicated spare parts kits (seals, glass joints, and vacuum grease).

Turnkey Solution Available: We also manufacture and supply matching Hermetic Refrigeration Heating Circulators (-30°C to 200°C) and Corrosion-Resistant Vacuum Pumps tailored for this 100L system to ensure plug-and-play operation.

Hot Tags: 100l pilot scale rotary evaporator, China 100l pilot scale rotary evaporator manufacturers, suppliers, factory